Image Analysis, Image Processing and Statistics
Measure the Facts in your Images
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Publications

Many publications have emerged from our projects in the past.

 

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Publications supported by Datinf GmbH

Journals


2013

Blum A, Ellwanger U, Luedtke H
Features Amplifying Dermoscopy (FAD) for better evaluation in difficult pigmented and non-pigmented melanocytic skin tumors J Dtsch Dermatol Ges. 2013 Oct 4. [Epub ahead of print]

2009

Christian Herdeg, MD; Katrin Göhring-Frischholz et al
Catheter-Based Delivery of Fluid Paclitaxel for Prevention of Restenosis in Native Coronary Artery Lesions After Stent Implantation
Circ Cardiovasc Intervent 2009;2;294-301

2008

Volz T, Caroli U, Lüdtke H, Bräutigam M, Kohler-Späth H, Röcken M, Biedermann T
Pimecrolimus cream 1% in erosive oral lichen planus--a prospective randomized double-blind vehicle-controlled study.
Br J Dermatol. 2008 Sep;159(4):936-41. Epub 2008 Jul 21. Erratum in: Br J Dermatol. 2008 Sep;159(4):994.

Christian Löfke, Till Ischebeck, Sabine König, Sabine Freitag and Ingo Heilmann
Alternative metabolic fates of phosphatidylinositol produced by PI-synthase isoforms in Arabidopsis thaliana
Biochemical Journal Immediate Publication. Published on 10 Apr 2008 as manuscript BJ20071371

Garbe C, Radny P, Linse R, Dummer R, Gutzmer R, Ulrich J, Stadler R, Weichenthal M, Eigentler T, Ellwanger U, Hauschild A.
Adjuvant low-dose interferon {alpha}2a with or without dacarbazine compared with surgery alone: a prospective-randomized phase III DeCOG trial in melanoma patients with regional lymph node metastasis.
Ann Oncol. 2008 Feb 14; [Epub ahead of print]

2007

Blume-Peytavi U, Kunte C, Krisp A, Bartels NG, Ellwanger U, Hoffmann R.
Comparison of the efficacy and safety of topical minoxidil and topical alfatradiol in the treatment of androgenetic alopecia in women.
J Dtsch Dermatol Ges. 2007 May;5(5):391-5.

2005

Maassen MM, Löwenheim H, Pfister M, Herberhold S, Jorge JR, Baumann I, Nüsser A, Zimmermann R, Brosch S, Zenner HP.
Surgical-handling properties of the titanium prosthesis in ossiculoplasty. Ear Nose Throat J. 2005 Mar;84(3):142-4, 147-9.

2004

Blum-A, Luedtke-H, Ellwanger-U, Schwabe-R, Rassner-G, Garbe-C
Digital image analysis for diagnosis of cutaneous melanoma. Development of a highly effective computer algorithm based on analysis of 837 melanocytic lesions.
Br J Dermatol. 2004 Nov;151(5):1029-38

Blum-A, Hofmann-Wellenhof-R, Luedtke-H, Ellwanger-U, Steins-A, Roehm-S, Garbe-C, Soyer-H
Value of the clinical history for different users of dermoscopy compared with results of digital image analysis.
J Eur Acad Dermatol Venereol. 2004 Nov;18(6):665-9

Blum-A, Vollert-B; Schlagenhauff-B (2004)
Visualization Method Based on Digital Image Analysis Reveals Photodamage of the Skin
Arch Dermatol 2004;140 1173-1174

2003

Hoffmann-R (2003)
TrichoScan: A Novel Tool For The Analysis of Hair Growth In Vivo.
Journal Invest Dermatol. 2003 Jun; 109-115.

Roehrig S, Tabbert A, Ferrando-May E. (2003)
In vitro measurement of nuclear permeability changes in apoptosis.
Anal Biochem. 2003 Jul 15;318(2):244-53.

2002

Hoffmann-R (2002)
TrichoScan. Ein neues Instrument für die digitale Haarzählung
Hautarzt. 2002 Dec;53(12):798-804

2001

Hoffmann-R (2001)
TrichoScan: combining epiluminescence microscopy with digital image analysis for the measurement of hair groth in vivo.
EUROPEAN-JOURNAL-OF-DERMATOLOGY. JUL-AUG 2001; 4(11) 362-368

1999

Blum A, Ellwanger U, Luedtke H, Garbe C (1999)
Digital image analysis of pigmented lesions. The Tuebinger Mole Analyser.
Skin Res Technol 1999 5:127.

Dissertations

2007

Jaworski S.
Dermatoskopie von Hauttumoren. Vergleich von vier Handdermatoskopen. Medizinische Fakultät der Eberhard-Karls-Universität zu Tübingen

Baerlecken NT
Weiteilsubstitution mit Hilfe von injizierten Präadipozyten-Fibrinkonstrukten
Medizinische Fakultät der Albert-Ludwigs-Universität Freiburg

Schnell R
Objektive Untersuchung von Hang-Over-Effekten mit dem Pupillographischen Schläfrigkeitstest (PST)
Medizinische Fakultät der Eberhard-Karls-Universität zu Tübingen

Dr. U. Ellwanger

Journals

2003

Dadras SS, Paul T, Bertoncini J, Brown LF, Muzikansky A, Jackson DG, Ellwanger U, Garbe C, Mihm MC, Detmar M. (2003)
Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival.
Am J Pathol. 2003 Jun;162(6):1951-60.

Garbe C, Leiter U, Ellwanger U, Blaheta HJ, Meier F, Rassner G, Schittek B. (2003)
Diagnostic value and prognostic significance of protein S-100beta, melanoma-inhibitory activity, and tyrosinase/MART-1 reverse transcription-polymerase chain reaction in the follow-up of high-risk melanoma patients.
Cancer. 2003 Apr 1;97(7):1737-45.

Garbe C, Paul A, Kohler-Späth H, Ellwanger U, Stroebel W, Schwarz M, Schlagenhauff B, Meier F, Schittek B, Blaheta HJ, Blum A, Rassner G (2003)
Prospective Evaluation of a Follow-Up Schedule in Cutaneous Melanoma Patients: Recommendations for an Effective Follow-Up Strategy.
J Clin Oncol. Feb 1 2003: 520-529.

2002

Willer J, Noack N, Ellwanger U, Hoffmann J (2002)
IMZ implants in the treatment of the shortened dental arch in the upper and lower jaws.
Schweiz Monatsschr Zahnmed. 112(11):1116-20. German.

Meier F, Will S, Ellwanger U, Schlagenhauff B, Schittek B, Rassner G, Garbe C (2002)
Metastatic pathways and time courses in the orderly progression of cutaneous melanoma.
Br J Dermatol. 147(1):62-70.

Garbe C, Ellwanger U, Tronnier M, Brocker EB, Orfanos CE (2002)
The New American Joint Committee on Cancer staging system for cutaneous melanoma: a critical analysis based on data of the German Central Malignant Melanoma Registry.
Cancer. Apr 15;94(8):2305-7.

2001

Schnorf M, Helfenstein U, Blum A, Ellwanger U, Garbe C, Burg G, Dummer R (2001)
Manifestations of the "pretherapeutic phase" of malignant melanoma of the skin in Switzerland 1996-1998.
Schweiz Rundsch Med Prax. 90(50):2193-8. German.

Schittek B, Blaheta HJ, Ellwanger U, Garbe C (2001)
Polymerase chain reaction in the detection of circulating tumour cells in peripheral blood of melanoma patients.
Recent Results Cancer Res. 158:93-104. Review.

Fuhrmann D, Lippold A, Borrosch F, Ellwanger U, Garbe C, Suter L (2001)
Should adjuvant radiotherapy be recommended following resection of regional lymph node metastases of malignant melanomas?
Br J Dermatol. 144(1):66-70.

Hauschild A, Garbe C, Stolz W, Ellwanger U, Seiter S, Dummer R, Ugurel S, Sebastian G, Nashan D, Linse R, Achtelik W, Mohr P, Kaufmann R, Fey M, Ulrich J, Tilgen W (2001)
Dacarbazine and interferon alpha with or without interleukin 2 in metastatic melanoma: a randomized phase III multicentre trial of the Dermatologic Cooperative Oncology Group (DeCOG).
Br J Cancer. Apr 20;84(8):1036-42.

2000

Schlagenhauff B, Schittek B, Ellwanger U, Stroebel W, Blum A, Schwarz M, Rassner G, Garbe C (2000)
Significance of serum protein S100 levels in screening for melanoma metastasis: does protein S100 enable early detection of melanoma recurrence?
Melanoma Res. 10(5):451-9.

Schlagenhauff B; Ellwanger U; Breuninger H; Stroebel W; Rassner C; Garbe C (2000)
Prognostic impact of the type of anaesthesia used during the excision of primary cutaneous melanoma.
Melanoma-Research 10 (2) : 165-169

Blaheta HJ; Ellwanger U; Schittek B; Sotlar K; Maczey E; Breuninger H; Thelen MH; Bueltmann B; Rassner G; Garbe C (2000)
Examination of regional lymph nodes by sentinel node biopsy and molecular analysis provides new staging facilities in primary cutaneous melanoma.
Journal of Investigative Dermatology 114 (4) : 637-642

1999

Blum A; Brand CU; Ellwanger U; Schlagenhauff B; Stroebel W; Rassner G; Garbe C (1999)
Awareness and early detection of cutaneous melanoma: an analysis of factors related to delay in treatment.
British Journal of Dermatology 141:783-787

Schittek-B; Bodingbauer Y; Ellwanger U; Blaheta HJ; Garbe C (1999)
Amplification of MelanA messenger RNA in addition to tyrosinase increases sensitivity of melanoma cell detection in peripheral blood and is associated with the clinical stage and the prognosis of malignant melanoma.
British Journal of Dermatology 141:30-36

Blaheta HJ; Schittek B; Breuninger H; Sotlar K; Ellwanger U; Thelen MH; Maczey E; Rassner G; Bueltmann B; Garbe C (1999)
Detection of melanoma micrometastasis in sentinel nodes by reverse transcription-polymerase chain reaction correlates with tumor thickness and is predictive of micrometastatic disease in the lymph node basin.
American Journal of Surgical Pathology. 23 (7):822-828.

1998

Metzger S; Ellwanger U; Stroebel W; Schiebel U; Rassner G; Fierlbeck G (1998)
Extent and consequences of physician delay in the diagnosis of acral melanoma.
Melanoma Research. 8 (2) : 181-186

Blaheta HJ; Schittek B; Breuninger H; Maczey E; Kroeber S; Sotlar K; Ellwanger U; Thelen MH; Rassner G; Bultmann B; Garbe C (1998)
Lymph node micrometastases of cutaneous melanoma: Increased sensitivity of molecular diagnosis in comparison to immunohistochemistry.
International Journal of Cancer. 79 (4) : 318-323.

Luther H, Garbe C, Ellwanger U, Altmeyer P:
Development of melanocytic nevi in children: Reply.
Arch Dermatol 133:1049.

Schlagenhauff B, Stroebel W, Ellwanger U, Garbe C:
Metastatic melanoma of unknown primary origin shows prognostic similarities to regional metastatic melanoma: recommendations for initial staging examinations.
Cancer 80:60-65

1997

Brand CU, Ellwanger U, Stroebel W, Meier F, Schlagenhauff B, Rassner G, Garbe C (1997)
Prolonged survival in disseminated malignant melanoma: an analysis of related prognostic factors.
Cancer 79: 2345-2353

Blum A, Ellwanger U, Garbe C (1997)
Seasonal patterns in the diagnosis of cutaneous malignant melanoma: analysis of the data of the German Central Malignant Melanoma Registry.
Br J Dermatol 136: 968-981

1996

Luther H, Altmeyer P, Garbe C, Ellwanger U, Jahn S, Hoffmann K, Segerling M (1996)
Increase of melanocytic nevus counts in children during 5 years of follow-up and analysis of associated factors.
Arch Dermatol 132:1473-8

1995

Garbe C, Büttner P, Ellwanger U, Orfanos CE:
Die Versorgung des primären Malignen Melanoms der Haut im deutschen Sprachraum in den Jahren 1983 bis 1993. Eine Studie des Zentralregister Malignes Melanom der Deutschen Dermatologischen Gesellschaft.
Hautarzt. 1995 Okt; 46(10): 762-70

Garbe C, Büttner P, Ellwanger U, Bröcker EB, Jung EG, Orfanos CE, Rassner G, Wolff HH:
Das Zentralregister Malignes Melanom der Deutschen Dermatologischen Gesellschaft in den Jahren 1983-1993. Epidemiologische Entwicklungen und aktuelle therapeutische Versorgung des malignen Melanoms der Haut.
Hautarzt. 1995 Okt; 46(10): 683-92

Contributions to books

Garbe C, Schittek B, Blaheta HJ, Ellwanger U, Schlagenhauff B, Breuninger H, Rassner G:
Molekulare Diagnose des malignen Melanoms.
In: Plettenberg A, Meigel WN, Moll I (Hrsg.) Dermatologie an der Schwelle zum neuen Jahrtausend, 1999, Berlin: Springer-Verlag, S, 482-485

Blaheta HJ, Schittek B, Sotlar K, Kröber S, Ellwanger U, Garbe C:
Molekularbiologischer Nachweis einer Mikrometastasierung an Lymphknotengewebe von Melanompatienten mittels Tyrosinase RT-PCR. In: Garbe C, Rassner G (Hrsg.)
Leitlinien und Qualitätssicherung für Diagnostik und Therapie, 1998, Berlin: Springer-Verlag, S. 278-279

Breuninger H, Stroebel W, Schlagenhauff B, Ellwanger U, Rassner G:
Follow-Up of Malignant Skin Tumors.
In: Altmeyer P, Hoffmann K, Stücker M (Hrsg.) Skin Cancer and UV Radiation, 1996, Berlin: Springer-Verlag, S.1233-1241

Blum A, Ellwanger U, Garbe C:
Seasonal Patterns in the Diagnosis of Cutaneous Malignant Melanoma due to Differential Detection Rather than Biological Causes. An Analysis of ther data of ther Germany Central Malignant Melanoma Registry.
In: Altmeyer P, Hoffmann K, Stücker M (Hrsg.) Skin Cancer and UV Radiation, 1996, Berlin: Springer-Verlag, S.519-526

Ellwanger U, Garbe C:
Recent Epidemiological Trends of Cutaneous Melanoma in Germany, Austria and Switzerland. Results of the Central Malignant Melanoma Registry.
In: Altmeyer P, Hoffmann K, Stücker M (Hrsg.) Skin Cancer and UV Radiation, 1996, Berlin: Springer-Verlag, S.507-518

Blum A, Ellwanger U, Garbe C:
Das Maligne Melanom der Haut. Analyse der Daten des Zentralregisters Malignes Melanom der Deutschen Dermatologischen Gesellschaft, 1983-1995. Krebsverband Baden-Württemberg e.V. Stuttgart, April 1996. (Broschüre)

Blum A, Ellwanger U, Garbe C:
Das Maligne Melanom der Haut. Analyse der Daten des Zentralregisters Malignes Melanom der Deutschen Dermatologischen Gesellschaft, 1983-1995. Krebsverband Baden-Württemberg e.V. Stuttgart, April 1996. (Broschüre)

Dr. H. Lüdtke

Journals

2009

Wilhelm B, Kellert R, Schnell R, Lüdtke H, Petrini O
Lack of sedative effects after vespertine intake of oxazepam as hypnotic in healthy volunteers
Psychopharmacology (Berl). 2009 Sep;205(4):679-88. Epub 2009 Jun 24.

Skorkovská K, Wilhelm H, Lüdtke H, Wilhelm B
How sensitive is pupil campimetry in hemifield loss?
Graefes Arch Clin Exp Ophthalmol. 2009 Jul;247(7):947-53. Epub 2009 Feb 19.

Skorkovská K, Lüdtke H, Wilhelm H, Wilhelm B
Pupil campimetry in patients with retinitis pigmentosa and functional visual field loss.
Graefes Arch Clin Exp Ophthalmol. 2009 Jun;247(6):847-53. Epub 2008 Dec 19.

Warga M, Lüdtke H, Wilhelm H, Wilhelm B
How do spontaneous pupillary oscillations in light relate to light intensity?
Vision Res. 2009 Feb;49(3):295-300. Epub 2008 Dec 19.

2008

Volz T, Caroli U, Lüdtke H, Bräutigam M, Kohler-Späth H, Röcken M, Biedermann T
Pimecrolimus cream 1% in erosive oral lichen planus--a prospective randomized double-blind vehicle-controlled study.
Br J Dermatol. 2008 Sep;159(4):936-41. Epub 2008 Jul 21. Erratum in: Br J Dermatol. 2008 Sep;159(4):994.

2007

Wilhelm H, Peters T, Lüdtke H, Wilhelm B
The prevalence of relative afferent pupillary defects in normal subjects
J Neuroophthalmol. 2007 Dec;27(4):263-7.

2006

Wilhelm B, Lüdtke H, Wilhelm H; BRAION Study Group
Efficacy and tolerability of 0.2% brimonidine tartrate for the treatment of acute non-arteritic anterior ischemic optic neuropathy (NAION): a 3-month, double-masked, randomised, placebo-controlled trial
Graefes Arch Clin Exp Ophthalmol. 2006 May;244(5):551-8. Epub 2005 Sep 8.

2005

Schmid R, Luedtke H, Wilhelm BJ, Wilhelm H
Pupil campimetry in patients with visual field loss
Eur J Neurol. 2005 Aug;12(8):602-8.

2004

Blum A, Luedtke H, Ellwanger U, Schwabe R, Rassner G, Garbe C
Digital image analysis for diagnosis of cutaneous melanoma. Development of a highly effective computer algorithm based on analysis of 837 melanocytic lesions
J Eur Acad Dermatol Venereol. 2004 Nov;18(6):665-9.

Schmid R, Ceurremans P, Luedtke H, Wilhelm BJ, Wilhelm HM
Effect of age on the pupillomotor field
J Neuroophthalmol. 2004 Sep;24(3):228-34.

2002

Wilhelm B, Körner A, Heldmaier K, Moll K, Wilhelm H, Lüdtke H (2002)
Do the results of the pupillographic sleepiness test depend on age and gender?
Journal of Sleep Research 2002: Vol. 11 Suppl.1 p.252

Lüdtke H, Warga M, Wilhelm H, Wilhelm B (2002)
Can the pupillographic sleepiness test be performed in light?
Journal of Sleep Research 2002: Vol. 11 Suppl.1 p.142

Lüdtke H, Neugebauer P, Hohenstein E, Ederle K (2002)
Pupillographischer Schläfrigkeitstest (PST) bei OSAS: Messverlauf und Beziehung zu subjektiver Schläfrigkeit.
Pneumologie 2002: 56: 55

2001

Wilhelm B, Lüdtke H, Wilhelm H (2001)
Wach oder schläfrig? Pupillographie zur Objektivierung von Tagesschläfrigkeit.
neuro-date 2001, 114: 22-24

Lüdtke H, Wilhelm B (2001)
An overview of the Pupillographic Sleepiness Test (PST)
Neuro-ophthalmology 25 (2001) 1-2:76

Weeß H G, Binder R, Grellner W, Lüdtke H, Wilhelm B, Steinberg R (2001)
Verkehrsgefährdung infolge Schläfrigkeit am Steuer Eine Untersuchung auf einer deutschen Bundesautobahn
Somnologie (2001) 5 (Suppl. 2), 1-64, S. 58

Lüdtke H, Heldmaier K, Moll K, Körner A, Wilhelm H, Wilhelm B (2001)
Prüfung anamnestischer Einflussgrößen auf den Pupillographischen Schläfrigkeitstest
Somnologie (2001) 5 (Suppl. 2), 1-64, S. 35

Wilhelm B, Körner A, Heldmaier K, Moll K, Wilhelm H, Lüdtke H (2001)
Normwerte des pupillographischen Schläfrigkeitstests für Frauen und Männer zwischen 20 und 60 Jahren.
Somnologie (2001) 5, 115 - 120

Wilhelm B, Giedke H, Lüdtke H, Bittner E, Hoffmann A, Wilhelm H (2001)
Daytime variations in central nervous system activation measured by a pupillographic sleepiness test.
Journal of Sleep Research (2001) 10, 1 - 7

 

Wilhelm B, Lüdtke H, Peters T, Schmid R, Wilhelm H, Zrenner E (2001)
Automatisierter Swinging-flashlight-Test bei Patienten mit Sehnervenerkrankungen.
Klin Monatsbl Augenheilk 2001; 218:21-25

 

2000

Helmut Wilhelm, Katrin Heldmaier, Kerstin Zimmermann, Andreas Körner, Holger Lüdtke, Barbara Wilhelm (2000)
Sind die Messergebnisse des pupillographischen Schläfrigkeitstests von Alter und Geschlecht abhängig?
Somnologie 4(Suppl. 1), 1-70, S. 42

Holger Lüdtke, Ernst Hohenstein, Petra Neugebauer, Barbara Wilhelm (2000)
Kann die Messzeit des pupillographischen Schläfrigkeitstests sinnvoll verkürzt werden?
Somnologie (2000) 4(Suppl. 1), 1-70, S. 42

Barbara Wilhelm, Max Warga, Holger Lüdtke, Peter Streicher (2000)
Die Veränderung schläfrigkeitsbedingter Pupillenoszillationen durch Lichteinfluss.
Somnologie (2000) 4(Suppl. 1), 1-70, S. 42

Holger Lüdtke, Andreas Körner, Barbara Wilhelm und Helmut Wilhelm (2000)
Reproduzierbarkeit des pupillographischen Schläfrigkeitstests bei gesunden Männern.
Somnologie 4:170-172

Wilhelm H, Neitzel J, Wilhelm B, Beuel S, Lüdtke H, Kretschmann U, Zrenner E. (2000)
Pupil perimetry using m-sequence stimulation technique. Invest.
Ophthal. Vis. Sci.: in Druck.

1999

Hunter J, John Milton, Holger Lüdtke, Barbara Wilhelm, Helmut Wilhelm (1999)
Spontaneous fluctuations in pupil size are not triggered by the near response.
Vision Research, Vol 40, Nr 5, pp.567-573.

Wilhelm B, Neugebauer P, Lüdtke H, Hohenstein E, Ederle K, Wilhelm H. (1999)
Pupillographischer Schläfrigkeitstest zur Therapiekontrolle beim Schlafapnoe-Syndrom nach drei Monaten nächtlicher Beatmung.
Somnologie 3, 53-56

Lüdtke H., Kriegbaum C., Leo-Kottler B., Wilhelm H. (1999)
Pupillary light reflexes in patients with Leber’s hereditary optic neuropathy
Graefe’s Arch Clin Exp Ophthalmol, 237: 207-211

1998

Wilhelm H, Lüdtke H, Wilhelm B. (1998)
Pupillographic sleepiness test applied in hypersomniacs and normals.
Graefe's Arch Clin Exp Opthalmol 236;725 - 729

Lüdtke H, Wilhelm B, Adler M, Schaeffel F, Wilhelm H. (1998)
Mathematical procedures in data recording and processing of pupillary fatigue waves.
Vis Res 38, 2889-2896

Wilhelm B, Rühle K-H, Widmaier D, Lüdtke H. (1998)
Objektivierung von Schweregrad und Therapieerfolg beim obstruktiven Schlafapnoe-Syndrom mit dem pupillographischen Schläfrigkeitstest.
Somnologie 2, 51-57.

Wilhelm B, Wilhelm H, Lüdtke H, Streicher P, Adler M. (1998)
Pupillographic assessment of sleepiness in sleep-deprived healthy subjects.
Sleep 21 (3), 258-265.

1996

Wilhelm H, Wilhelm B, Lüdtke H. (1996)
Pupillographie – Prinzipien und Anwendungsmöglichkeiten.
Z prakt Augenheilkd, 17:327-336

Wilhelm B, Wilhelm H, Streicher P, Lüdtke H, Adler M. (1996)
Pupillographie als objektiver Vigilanztest.
Wien Med Wschr. 146:387-389

Wilhelm B, Wilhelm H, Lüdtke H, Adler M, Streicher P (1996)
Pupillographie zur objektiven Vigilanzprüfung - methodische Probleme und Lösungsansätze.
Ophthalmologe 93:446-450

Buchbeiträge

Wilhelm H, Wilhelm B, Lüdtke H.
Pupillography – principles and applications in basic and clinical research.
In: Kuhlmann J, Böttcher M. (Edts.) Pupillography: principles, methods and applications. Zuckschwerdt Verlag, München 1999; S. 1-10

Wilhelm B, Lüdtke H, Wilhelm H.
Spontaneous pupillary oscillations – An objective measure for the level of tonic central nervous activation.
In: Kuhlmann J, Böttcher M. (Edts.) Pupillography: principles, methods and applications. Zuckschwerdt Verlag, München 1999; S. 27-36